Ichthyosis hystrix is a localized variant of Bullous Congenital Ichthyosiform Erythroderma by Broq, and also, localized form of Epidermolytic hyperkeratosis according to Frost and. Van Scott´s classification of ichthyosi-form dermatoses.
Clinically it is generally considered to be widespread systematized epidermal nevus, and demonstrating an autosomal dominant pattern of inheritance, and characterized by verrucous´ scale at or shortly after birth with particular involvement of flexural areas. A case of 21 year old girl with ichthyosis hystrix was reported. The skin lesion showed multiple rice to pea sized linear verrucous papules on left forearm, neck, axilla and upper chest.
The skin biopsy was done, the finding shows remarked laminated hyperkeratosis, acanthosis, papillomatosis, and vacuolization on malpighian layer.
Diagnosis was confirmed by clinical apperance and histopathological finding.
The method of treatment is 0.05 % Vitamin A acid ointment application and show marked improvement.
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